David Lloyd DSc

2008

• Gray, V. L.et al. 2008. Peptones from diverse sources: pivotal determinants of bacterial growth dynamics. Journal of Applied Microbiology 104(2), pp. 554-565. (10.1111/j.1365-2672.2007.03577.x)

• Amoroso, A. J.et al. 2008. 3-Chloromethylpyridyl bipyridine fac-tricarbonyl rhenium: a thiol-reactive luminophore for fluorescence microscopy accumulates in mitochondria. New Journal of Chemistry 32(7), pp. 1097-1102. (10.1039/b802215a)

• Aon, M. A.et al. 2008. The scale-free dynamics of eukaryotic cells. PLoS ONE 3(11) (10.1371/journal.pone.0003624)

• Lloyd, D. 2008. Biological time is fractal: early events reverberate over a life time. Journal of Biosciences 33(1), pp. 9-19. (10.1007/s12038-008-0017-8)

• Lloyd, D. and Rossi, E. L. 2008. Epilogue: a new vision of life. In: Lloyd, D. and Rossi, E. L. eds. Ultradian Rhythms from Molecules to Mind.. Springer, pp. 431., (10.1007/978-1-4020-8352-5_18)

• Brodsky, V. Y. and Lloyd, D. 2008. Self-organized intracellular ultradian rhythms provide direct cell-cell communication. In: Lloyd, D. and Rossi, E. L. eds. Ultradian Rhythms from Molecules to Mind: A New Vision of Life., Vol. I. The Netherlands: Springer, pp. 85-104., (10.1007/978-1-4020-8352-5_3)

• Lloyd, D.et al. 2008. The ultradian clock (~40 min) in yeast (Saccharomyces cerevisiae). In: Lloyd, D. and Rossi, E. L. eds. Ultradian Rhythms from Molecules to Mind: A New Vision of Life., Vol. I. Netherlands: Springer, pp. 11-42., (10.1007/978-1-4020-8352-5_1)

• Oscillations, Synchrony and deterministic chaos.D. Lloyd in (Lüttge, et al eds.) Vol. , 69-91 (2008).

• Respiratory oscillations in Yeasts. In: , (eds. M. Maroto and N.Monk). Landes Bioscience D.Lloyd (2006) and Adv. ExpH Med. Biol. , 118-140 (2008)

• The scale-free dynamics of eukaryotic cells. Aon MA, Roussel MR, Cortassa S, O'Rourke B, Murray DB, Beckmann M, Lloyd D. PLoS ONE. 2008 3(11):e3624

 

2007

• Amoroso, A. J.et al. 2007. Rhenium fac tricarbonyl bisimine complexes: biologically useful fluorochromes for cell imaging applications. Chemical Communications(29), pp. 3066-3068. (10.1039/b706657k)

• Lemar, K. M.et al. 2007. Diallyl disulphide depletes glutathione in Candida albicans: oxidative stress-mediated cell death studied by two-photon microscopy. Yeast 24(8), pp. 695-706. (10.1002/yea.1503)

• Murray, D. B. and Lloyd, D. 2007. A tuneable attractor underlies yeast respiratory dynamics. Biosystems 90(1), pp. 287-294. (10.1016/j.biosystems.2006.09.032)

• Roussel, M. and Lloyd, D. 2007. Observation of a chaotic multioscillatory metabolic attractor by real-time monitoring of a yeast continuous culture. FEBS Journal 274(4), pp. 1011-1018. (10.1111/j.1742-4658.2007.05651.x)

• Lloyd, D. and Murray, D. B. 2007. Redox rhythmicity: clocks at the core of temporal coherence. Bioessays 29(5), pp. 465-473. (10.1002/bies.20575)

• Aon, M. A.et al. 2007. Single and cell population respiratory oscillations in yeast: a 2-photon scanning laser microscopy study. FEBS Letters 581(1), pp. 8-14. (10.1016/j.febslet.2006.11.068)

• H2 Production in the Fish Parasite, Spironucleus vortens Millet CO, Cable J, Lloyd D. Protistology 2007 5 (1):55

• Trichomonas vaginalis and Giardia intestinalis produce Nitric Oxide: does Nitrosylation Induce Carbohydrate Metabolism ? Harris KM , Goldberg B, van der Giezen M, Biagini GA, Lloyd D. Protistology 2007 5 (1):36

• Evolution of eukaryotic Life:Oscillations, Rhythms and Clocks are a Necessity. Lloyd D ,Aon MA ,Murray DB ,Cortassa S Protistology 2007 5 (1):51

• Single and cell population respiratory oscillations in yeast: A 2-photon scanning laser microscopy study. (2007) Aon, M.A., Cortassa, S. Lemar, K.M., Hayes, A.J., Cortassa, S. and Lloyd D. , 8-14. (2007).

• Trichomonas vaginalis and Giardia intestinalis produce nitric oxide and display NO-synthase activity. (2006) K.M.Harris, B.Goldberg, G.C.Biagini and D.Lloyd. Protistology 53, (S1) 5182-5183

• The effect of temperature in methane dynamics in soil and peat cores: calculations from membrane inlet mass spectrometry. S.K.Sheppard, M. Beckmann, D.Lloyd. (2007) Canad. J. Soil Sci. , 11-22

 

2006

• Scheerer, S., Gomez, F. and Lloyd, D. 2006. Bioluminescence of Vibrio fischeri in continuous culture: Optimal conditions for stability and intensity of photoemission. Journal of Microbiological Methods 67(2), pp. 321-329. (10.1016/j.mimet.2006.04.010)

• Lloyd, D. 2006. Hydrogen sulfide: clandestine microbial messenger?. Trends in Microbiology 14(10), pp. 456-462. (10.1016/j.tim.2006.08.003)

• Gray, V. L.et al. 2006. Low tyrosine content of growth media yields aflagellate Salmonella enterica serovar Typhimurium. Microbiology 152(1), pp. 23-28. (10.1099/mic.0.28442-0)

• Lloyd, D. and Murray, D. B. 2006. Corrigendum to "the temporal architecture of eukaryotic growth" [FEBS Lett. 580 (2006) 2830-2835]. FEBS Letters 580(18), pp. 4571-4571. (10.1016/j.febslet.2006.07.026)

• Lloyd, D. 2006. Ultradian rhythms and clocks in plants and yeast. Biological Rhythm Research 37(4), pp. 281-296. (10.1080/09291010600804379)

• Lloyd, D. and Murray, D. B. 2006. The temporal architecture of eukaryotic growth. FEBS Letters 580(12), pp. 2830-2835. (10.1016/j.febslet.2006.02.066)

• Sayanova, O.et al. 2006. A bifunctional Δ12,Δ15-Desaturase from Acanthamoeba castellanii directs the synthesis of highly unusual n-1 series unsaturated fatty acids. Journal of Biological Chemistry 281(48), pp. 36533-36541. (10.1074/jbc.M605158200)

• Lloyd, D. 2006. The ultradian clock: not to be confused with the cell cycle. Nature Reviews Molecular Cell Biology 7(12) (10.1038/nrm1980-c1)

• Harris, K.et al. 2006. Trichomonas vaginalis and Giardia intestinalis Produce Nitric Oxide and Display NO-Synthase activity. Journal of Eukaryotic Microbiology 53(s1), pp. S182-S183. (10.1111/j.1550-7408.2006.00224.x)

• Deterministic chaos and rhythms in unicellular organisms. In: (eds. S. Mancuso and S. Shabala), Springer-Verlag, Berlin. Lloyd D. (2006).

• Peptones from diverse sources, pivotal deteminants of bacterial growth dynamics. V.L.Gray, C.T.Müller, I.D.Watkins, D.Lloyd. (2006).

• The Bioluminescence of : optimal conditions for stability and intensity of photoemission. S.Scheerer, F. Gomez and D.Lloyd. . J. Microbial. Methods 67, 321-329 (2006)

 

2005

• Lemar, K. M.et al. 2005. Allyl alcohol and garlic (Allium sativum) extract produce oxidative stress in Candida albicans. Microbiology 151(10), pp. 3257-3265. (10.1099/mic.0.28095-0)

• Sheppard, S. K.et al. 2005. The impact of sludge amendment on gas dynamics in an upland soil: monitored by membrane inlet mass spectrometry. Bioresource Technology 96(10), pp. 1103-1115. (10.1016/j.biortech.2004.10.006)

• Lloyd, D. and Murray, D. B. 2005. Ultradian metronome: timekeeper for orchestration of cellular coherence. Trends in Biochemical Sciences 30(7), pp. 373-377. (10.1016/j.tibs.2005.05.005)

• Systems dynamics of biology. D.Lloyd. J. Appl. Biomed., 1-12 (2005).

• The impact of sludge amendment on methanogen community structure in an upland soil. S.K.Sheppard, A.M.McCarthy, J.P.Loughnane, N.D.Gray, I.M.Head & D.Lloyd. Appl. Soil. Ecol. 28, , 147-162 (2005).

• Mass spectrometric monitoring of gas dynamics in peat monoliths: effects of temperature and diurnal cycles on emissions. M.Beckmann, S.K.Sheppard and D.Lloyd. Atmospheric Environ. 38, 6907-6913 (2005).

 

2004

• Beckmann, M., Sheppard, S. K. and Lloyd, D. 2004. Mass spectrometric monitoring of gas dynamics in peat monoliths: effects of temperature and diurnal cycles on emissions. Atmospheric Environment 38(39), pp. 6907-6913. (10.1016/j.atmosenv.2004.08.004)

• Pooley, D. T.et al. 2004. Continuous culture of photobacterium. Biosensors and Bioelectronics 19(11), pp. 1457-1463. (10.1016/j.bios.2003.09.003)

• Turner, N. A.et al. 2004. Resistance, biguanide sorption and biguanide-induced pentose leakage during encystment of Acanthamoeba castellanii. Journal of Applied Microbiology 96(6), pp. 1287-1995. (10.1111/j.1365-2672.2004.02260.x)

• Anaerobic protists: some misconceptions and confusions. D. Lloyd. (2004) Microbiology 150 (5) 1115-6

• Menadione kills Giardia intestinalis trophozoites and cysts. T.Paget, S.Maroulis, A. Mitchell, M.R.Edwards, E.L.Jarroll & D.Lloyd. Microbiology 1231-1236 (2004)

• Ultradian clock timekeeping: periodic quasiperiodic and chaotic outputs.D.Lloyd, A.L.Lloyd, L.F.Olsen, M.Stolyarov, E.I.Volkov & D.B.Murray. WSEAS Trans. Biol. Biomed. , 390-394 (2004)

• The plasma membrane of microaerophilic protists: oxidative and nitrosative stress (2004).D. Lloyd, J.C. Harris, G. A. Biagini, M. R. Hughes, S. Maroulis, C. Bernard, R. B. Wadley & M. R. Edwards. Microbiology, , 1183-1190 (2004).

 

2003

• Gray, N. D.et al. 2003. Effects of soil improvement treatments on bacterial community structure and soil processes in an upland grassland soil. FEMS Microbiology Ecology 46(1), pp. 11-22. (10.1016/S0168-6496(03)00160-0)

• Lloyd, D.et al. 2003. Nitrosative stress induced cytotoxicity in Giardia intestinalis. Journal of Applied Microbiology 95(3), pp. 576-583. (10.1046/j.1365-2672.2003.02008.x)

• Lloyd, D.et al. 2003. Respiratory oscillations in yeast: mitochondrial reactive oxygen species, apoptosis and time; a hypothesis. FEMS Yeast Research 3(4), pp. 333-339. (10.1016/S1567-1356(03)00071-0)

• Adams, C. A.et al. 2003. The Gts1 protein stabilizes the autonomous oscillator in yeast. Yeast 20(6), pp. 463-470. (10.1002/yea.976)

• Biagini, G. A.et al. 2003. Bacterial-like energy metabolism in the amitochondriate protozoon Hexamita inflata. Molecular and Biochemical Parasitology 128(1), pp. 11-19. (10.1016/S0166-6851(03)00025-2)

• Pooley, D. T.et al. 2003. Biological effects of millimeter-wave radiation: A high-throughput screening system. Review of Scientific Instruments 74(3), pp. 1296-1302. (10.1063/1.1542665)

• Lloyd, D. 2003. Effects of uncoupling of mitochondrial energy conservation on the ultradian clock-driven oscillations in Saccharomyces cerevisiae continuous culture. Mitochondrion 3(3), pp. 139-146. (10.1016/j.mito.2003.08.002)

• Murray, D. B., Klevecz, R. R. and Lloyd, D. 2003. Generation and maintenance of synchrony in Saccharomyces cerevisiae continuous culture. Experimental Cell Research 287(1), pp. 10-15. (10.1016/S0014-4827(03)00068-5)

• Lemar, K. M.et al. 2003. Cell death mechanisms in the human opportunistic pathogen Candida albicans. Journal of Eukaryotic Microbiology 50(s1), pp. 685-686. (10.1111/j.1550-7408.2003.tb00687.x)

• Iron-sulphur proteins in anaerobic eukaryotes. R. Cammack, D.S. Horner, M. van der Giezen, J. Kulda & D. Lloyd.In: Physiology and biochemistry of anaerobic bacteria.L. Ljungdahl, M.W.W. Adams, L.L. Barton, J.G. Ferry & M.K. Johnson (ed.) pp. 113-127, Springer, N.Y. (2003)

• Mass spectrometric monitoring of gas dynamics in peat cores: effects of temperature and diurnal cycles on emission?M. Beckmann, S.K.Sheppard & D. Lloyd.Atmospheric Environ. , 6907-6913.

 

2002

• Rutter, A. J.et al. 2002. Oxygen induction of a novel fatty acid n-6 desaturase in the soil protozoon, Acanthamoeba castellanii. Biochemical Journal, pp. 57-67. (10.1042/BJ20020189)

• Lemar, K. M., Turner, M. P. and Lloyd, D. 2002. Garlic (Allium sativum) as an anti-Candida agent: a comparison of the efficacy of fresh garlic and freeze-dried extracts. Journal of Applied Microbiology 93(3), pp. 398-405. (10.1046/j.1365-2672.2002.01707.x)

• Lloyd, D., Williams, A. S. and James, C. J. 2002. Nitrite inhibits hydrogen production and kills the cattle parasite Tritrichomonas foetus. Journal of Applied Microbiology 93(3), pp. 492-496. (10.1046/j.1365-2672.2002.01716.x)

• Sheppard, S. K. and Lloyd, D. 2002. Effects of soil amendment on gas depth profiles in soil monoliths using direct mass spectrometric measurement. Bioresource Technology 84(1), pp. 39-47. (10.1016/S0960-8524(02)00012-3)

• Lloyd, D.et al. 2002. Respiratory oscillations in yeast: clock-driven mitochondrial cycles of energization. FEBS Letters 519(1-3), pp. 41-44. (10.1016/S0014-5793(02)02704-7)

• Lloyd, D. and Harris, J. C. 2002. Giardia: highly evolved parasite or early branching eukaryote?. Trends in Microbiology 10(3), pp. 122-127. (10.1016/S0966-842X(02)02306-5)

• Sheppard, S. K. and Lloyd, D. 2002. Diurnal oscillations in gas production (O2, CO2, CH4, and N2) in soil monoliths. Biological Rhythm Research 33(5), pp. 577-591. (10.1076/brhm.33.5.577.13937)

• Williams, A. G.et al. 2002. Factors affecting the activity of enzymes involved in peptide and amino acid catabolism in non-starter lactic acid bacteria isolated from Cheddar cheese. International Dairy Journal 12(10), pp. 841-852. (10.1016/S0958-6946(02)00063-8)

• Lloyd, D. 2002. Noninvasive methods for the investigation of organisms at low oxygen levels. Advances in Applied Microbiology 51, pp. 155-174. (10.1016/S0065-2164(02)51005-4)

• Kumar, R. and Lloyd, D. 2002. Recent advances in the treatment of Acanthamoeba keratitis. Clinical Infectious Diseases 35(4), pp. 434-441. (10.1086/341487)

• Salgado, E., Murray, D. B. and Lloyd, D. 2002. Some antidepressant agents (Li+, monoamine oxidase type A inhibitors) perturb the ultradian clock in Saccharomyces cerevisiae. Biological Rhythm Research 33(3), pp. 351-361. (10.1076/brhm.33.3.351.8256)

• Sheppard, S. K. and Lloyd, D. 2002. Direct mass spectrometric measurement of gases in soil monoliths. Journal of Microbiological Methods 50(2), pp. 175-188. (10.1016/S0167-7012(02)00025-8)

• Harris, M. J.et al. 2002. Detection of living cells in stratospheric samples. Presented at: Instruments, methods, and missions for astrobiology IV, San Diego, CA, 29-30 July 2001 Presented at Hoover, R. B. et al. eds.Instruments, methods, and missions for astrobiology IV : 29-30 July, 2001, San Diego, [California] USA. SPIE Proceedings Series Vol. 4495. Bellingham, WA: Society of Photo-optical Instrumentation Engineers pp. 192-198., (10.1117/12.454758)

• Lloyd, D.et al. 2002. Direct interface of chemistry to microbiological systems: membrane inlet mass spectrometry. Journal of Microbiological Methods 48(2-3), pp. 289-302. (10.1016/S0167-7012(01)00331-1)

• Suller, M. T. E. and Lloyd, D. 2002. The antibacterial activity of vancomycin towards Staphylococcus aureus under aerobic and anaerobic conditions. Journal of Applied Microbiology 92(5), pp. 866-872. (10.1046/j.1365-2672.2002.01594.x)

• Wickramasinghe, N. C., Lloyd, D. and Wickramasinghe, J. T. 2002. Evidence of photoluminescence of biomaterial in space. Presented at: Instruments, methods, and missions for astrobiology IV, San Diego, CA, 29-30 July 2001 Presented at Hoover, R. B. et al. eds. Instruments, methods, and missions for astrobiology IV : 29-30 July, 2001, San Diego, [California] USA. SPIE Proceedings Series Vol. 4495. Bellingham, WA: Society of Photo-optical Instrumentation Engineers pp. 255-260., (10.1117/12.454762)

• Lloyd, D., Ralphs, J. R. and Harris, J. C. 2002. Hydrogen production in Giardia intestinalis, a eukaryote with no hydrogenosomes. Trends in Parasitology 18(4), pp. 155-156. (10.1016/S1471-4922(01)02174-2)

• Antibacterial activity of Vancomycin towards Staphylococcus sapens under aerobic and anaerobic conditions.  Suller, M. T. E. & Lloyd, D. J. Med. Microbiol. 92, 866-872 (2002).

• An Introduction to Metabolic and CellularEngineering, (S. Cortassa, M.A. Aon, A.A. Inglesias, D. Lloyd).  World Scientifice, Singapore (2002).

• Biogenic controls on trace gas fluxes in Northern Wetlands.  T.Christiansen, D. Lloyd et al. IGBP Global Change Newsletter (2002) 51, 16, 9-15.

• Boiling muds and scalding soils: new species and enzymes for the future.D. Lloyd 64-66 (2002).

• Non-invasive methods and the investigation of organisms at low O2 levels.D. Lloyd. Adv. Appl. Microbiol. 51, 155-183 (2002).

• Current trends in research into the waterborne parasite, Giardia. S. Lane & D. Lloyd. Crit. Rev. Microbiol. 28, 123-147, (2002).

• Tribute: Professor V. Ya Brodsky.D. Lloyd, K. Hammond, J. Calvert-Evers, D. Gilbert & C. Ferreira.. , 960-961 (2002).

• Wales is not part of England. W. H. Evans & D. Lloyd. 797 (2002).

• Oxygen Homeodynamics in Giardia.  In: “Giardia a Cosmopolitan Organism” ed. B. E. Olson, M. E. Olsen & P. Wallis, CAB International (2002).

• Allium sativum (Garlic) and some of its components are effective antigiardials in vitro. In: “Giardia a Cosmopolitan Organism” ed. B. E. Olson, M. E. Olsen & P. Wallis, CAB International (2002).

• Cycles of mitochondrial energization driven by the ultradian clock in a culture of Saccharomyces cerevisiae. D. Lloyd, L. E. J. Salgado, M. P. Turner, M. T. E. Suller and D. Murray. Microbiology.  148 3715-3724 (2002).

• Progress rowards vindication of panspermia. N. C. Wickramasinghe, M. Wainwright, J. V. Narlikar, P. Rajaratnam, M.J.Harris & D. Lloyd. Astron. Space Res. 283, 403-413 (2002).

• Detection of extraterrestial life in stratospheric samples.  D. Lloyd, N. C. Wickramasinghe, M. J. Harris, J. V. Narlikar, P. Rajaratnam, P. Bhargava, S. Shivaji, G.S.N. Reddy, M.P. Turner, A. Al-Mufti, M.K. Wallis, S. Ramadurai & F. Hoyle. ‘Multicolour Universe’  Proceedings of the International Conference, Sep 7-10, 2001. Mumbai. (Ed.) R.K. Manchanda & B.Paul. pp. 367-374 (2002).

• The “primitive” microaerophile Giardia intestinalis (Syn. lamblia, duodenalis) has specialized membranes with electron transport and membrane-potential-generating functions.  D. Lloyd, J.C. Harris, S. Maroulis, R. Wadley, J.R. Ralphs, Ao. C. Hann, M. Turner, M. Edwards. Microbiology, 148, 1349-1354 (2002).

 

2001

• Murray, D. B.et al. 2001. Clock control of ultradian respiratory oscillation found during yeast continuous culture. Journal of Bacteriology 183(24), pp. 7253-7259. (10.1128/JB.183.24.7253-7259.2001)

• Harris, J., Plummer, S. and Lloyd, D. 2001. Antigiardial drugs. Applied Microbiology and Biotechnology 57(5-6), pp. 614-619. (10.1007/s002530100720)

• Harris, J. C.et al. 2001. Antimicrobial properties of Allium sativum (garlic). Applied Microbiology and Biotechnology 57(3), pp. 282-286. (10.1007/s002530100722)

• Connell, C.et al. 2001. Encystation of Acanthamoeba castellanii: dye uptake for assessment by flow cytometry and confocal laser scanning microscopy. Journal of Applied Microbiology 90(5), pp. 706-712. (10.1046/j.1365-2672.2001.01296.x)

• Tammam, J. D.et al. 2001. Membrane inlet mass spectrometric measurement of O2 and CO2 gradients in cultures of Lactobacillus paracasei and a developing Cheddar cheese ecosystem. International Journal of Food Microbiology 65(1-2), pp. 11-22. (10.1016/S0168-1605(00)00438-4)

• Lloyd, D. and Wallis, P. 2001. A Giardia feast. Trends in Parasitology 17(3), pp. 115-117. (10.1016/S1471-4922(00)01873-0)

• Goldberg, B.et al. 2001. In situ kinetic characterization of methylthioadenosine transport by the adenosine transporter (P2) of the African Trypanosoma brucei brucei and Trypanosoma brucei rhodesiense. Biochemical Pharmacology 61(4), pp. 449-457. (10.1016/S0006-2952(00)00560-8)

• Morgan, J.et al. 2001. Rapid and sensitive quantitation of antibiotics in fermentations by electrospray mass spectrometry. Rapid Communications in Mass Spectrometry 15(14), pp. 1229-1238. (10.1002/rcm.368)

• Beckmann, M. and Lloyd, D. 2001. Mass spectrometric monitoring of gases (CO2', CH4', O2) in a mesotrophic peat core from Kopparas Mire, Sweden. Global Change Biology 7(2), pp. 171-180. (10.1046/j.1365-2486.2001.00396.x)

• Cross, R.et al. 2001. Enzymatic removal of nitric oxide catalyzed by cytochrome c' in rhodobacter capsulatus. Journal of Bacteriology 183(10), pp. 3050-3054. (10.1128/JB.183.10.3050-3054.2001)

• Beckmann, M. and Lloyd, D. 2001. Extraction and identification of volatile organic substances (VOS) from Scottish peat cores. Atmospheric Environment 35(1), pp. 79-86. (10.1016/S1352-2310(00)00290-9)

• The detection of living cells in stratospheric samples  M. J. Harris, N. C. Wickramasinghe, D. Lloyd, J. V. Narlikar, P. Rajaralnam, M. P. Turner, S. Al-Mufti, M. K. Wallis, S. Ramadurai, F. F. Hoyle.  Instru. Meth. Missions Astron 4449 (2001)

• Evidence of photoluminescence of biomaterial in space.  N.C. Wickramasinghe, D. Lloyd & J. T. Wickramasinghe.  Instru. Meth. Missions Astron (2001).

• The antioxidant potential of pyruvate in the amitochondriate diplomonads Giardia intestinalis and Hexamita inflata.  G. A. Biagini, J. H. Park, D. Lloyd & M. R. Edwards.  Microbiology, 147, 3359-3365 (2001).